Sign In

Why Multilingual Site Training Matters in Global Clinical Trials

Training clinical site staff in their native languages is essential to ensure consistent study execution and regulatory compliance across global trial locations. As clinical trials become increasingly multinational, language barriers can lead to misinterpretation of protocols, inconsistent procedures, and avoidable deviations that jeopardize data quality and patient safety.

High-quality translation of site training materials helps investigator teams fully understand study objectives, operational workflows, and Good Clinical Practice (GCP) requirements. This reduces onboarding time, minimizes protocol violations, and supports faster and more efficient site activation.

The demand for multilingual site training is also increasing with the rise of decentralized, hybrid, and remote trial models. Investigator teams often access onboarding materials and protocol briefings through digital formats, including interactive eLearning modules, virtual investigator meetings, and mobile-optimized training apps. These formats require accurate localization that preserves both content clarity and technical functionality.

Sesen provides specialized translation services for clinical site training materials in over 150 languages. We support sponsors and CROs with linguistically precise, audit-ready training content optimized for both static documents and digital learning environments. Our end-to-end capabilities help ensure operational consistency, regulatory compliance, and faster site readiness across global trials.

Read More Read Less

Types of Site Training Materials We Translate

Sesen translates a comprehensive range of clinical site training materials to support global study readiness, regulatory compliance, and operational consistency. Our linguists specialize in medical and regulatory content, ensuring accuracy, cultural relevance, and adherence to health authority standards across all languages. We localize both static and interactive formats, including content designed for digital onboarding, eLearning, and mobile training platforms.

Translation of SOPs governing site operations, protocol adherence, adverse event reporting, and trial-specific workflows. We ensure alignment with ICH GCP, FDA, EMA, and local regulatory requirements.

Translation of presentation slides and speaker notes used during investigator meetings, site initiation visits, and remote site briefings. Visual content and embedded annotations are localized for full comprehension.

Localization of study protocols, lab manuals, drug preparation guides, and visit schedules to ensure that investigator teams follow consistent procedures across trial sites.

Multilingual translation of orientation materials and study-specific onboarding packets. Content is optimized for both printed and digital formats, enabling quick distribution across global sites.

Translation of staff-facing training modules that explain informed consent processes, documentation standards, and patient communication protocols.

Accurate translation of materials used to train site staff on pharmacovigilance procedures, SAE reporting, protocol deviations, and regulatory updates.

Localization of recorded webinars, instructional videos, and site training tutorials. We provide both multilingual subtitles and native-language voiceovers for clear, accessible delivery.

Translation and localization of LMS-ready eLearning content, including SCORM 1.2, SCORM 2004, xAPI, and HTML5-based modules. We also support interactive formats optimized for mobile delivery and rapid site onboarding.

Sesen supports all major content formats and training delivery systems, ensuring seamless localization and deployment across your LMS, investigator portals, and mobile learning platforms

How We Support Global Site Training

Sesen delivers expert translation services tailored to the demands of multilingual site training for global clinical trials. Our approach combines deep clinical knowledge with scalable translation workflows to ensure training materials are accurate, regulatory-compliant, and fully optimized for digital deployment across global sites.

All translations are performed by linguists with experience in clinical research, GCP guidelines, and relevant therapeutic areas. Our teams understand the scientific and regulatory context of site training materials, from oncology protocols to vaccine trials.

We apply standardized terminology and controlled language techniques to maintain consistency across materials and regions. This is essential for preventing miscommunication and reducing variability in site-level interpretation.

Our processes are aligned with international regulatory requirements, including ICH E6 (R2), EMA, FDA, and local ethics board expectations. We provide traceability and documentation to support audit readiness and submission workflows.

Sesen supports the translation of content used in eLearning platforms, virtual investigator meetings, and mobile training applications. Our workflows accommodate SCORM, xAPI, and other digital formats to ensure seamless integration into your learning infrastructure.

By combining linguistic precision with technical adaptability, Sesen helps sponsors and CROs deliver high-impact, multilingual training that accelerates site readiness and strengthens compliance across regions.

Our Translation and Review Process

Sesen follows a rigorous translation and quality assurance process tailored specifically to the requirements of global clinical site training. Our workflow ensures linguistic accuracy, regulatory alignment, and formatting integrity across all target languages and digital platforms.

Every training document undergoes a structured three-step process. Each phase is handled by a separate linguist with proven expertise in life sciences and clinical research. This division of roles ensures objective review, accurate terminology, and stylistic consistency aligned with GCP and study-specific protocols.

Our production team preserves the original layout, slide design, and visual hierarchy while adapting content for multilingual delivery. We optimize line breaks, font scaling, and screen-length balance to maintain clarity across all languages and devices, including mobile and LMS environments.

We provide optional bilingual quality checks and in-context reviews to validate translations directly within the final digital environment. Whether deployed in a web-based LMS, virtual investigator meeting platform, or mobile app, we ensure that translated content functions as intended and supports user comprehension.

In addition to our human-led QA, we leverage SesenGPT, our proprietary AI engine trained exclusively on life sciences content, to perform automated linguistic checks at scale. SesenGPT reviews translations for terminology consistency, formatting issues, and common linguistic errors, enabling our reviewers to focus on high-impact refinements. This hybrid approach improves turnaround time and enhances quality assurance without compromising regulatory standards.

Sesen’s multi-step QA process delivers site training translations that meet the highest standards for clarity, accuracy, and operational effectiveness in global trials.

Integrations with Learning Platforms

Sesen supports seamless integration of translated site training materials into leading eLearning systems used across global clinical trials. Our workflows are optimized for digital training delivery, ensuring compatibility with popular authoring tools, LMS platforms, and multimedia formats.

We work with a wide range of eLearning platforms and authoring tools, including Articulate Storyline, Rise 360, Moodle, Adobe Captivate, and more. Our translations preserve all visual and functional elements to ensure readiness for direct upload and deployment.

Sesen provides full localization of SCORM and xAPI-compliant training modules. We maintain structural integrity across all course components, including metadata, interactive elements, navigation logic, and assessments, so that multilingual versions perform consistently in your LMS.

For video-based training modules, we offer professional subtitle translations and synchronized voiceovers recorded by native speakers. All voice tracks are time-aligned to ensure clear delivery of key concepts across languages.

SesenGPT-powered tools accelerate audio localization with high-quality synthetic voiceovers, voice cloning, and timing automation. These AI-enhanced solutions support rapid deployment while preserving audio clarity and tone across multiple languages.

By combining linguistic precision with technical integration, Sesen enables sponsors and CROs to scale clinical site training efficiently across global regions and digital channels.

Regulatory Compliance and Standards

Sesen’s translation workflows are purpose-built to meet the rigorous regulatory requirements of clinical trials. We ensure that all translated site training materials support Good Clinical Practice (GCP) and are ready for inspection by health authorities across global regions.

All translations adhere to GCP principles, ensuring that site staff are trained using consistent and accurate information in their native languages. Our documentation and QA processes are structured to support audit readiness and inspection by sponsors, CROs, IRBs, and regulatory agencies.

We maintain full traceability of each translation project, including linguist qualifications, role assignments, version history, and review logs. This structured audit trail provides clear accountability and supports compliance with sponsor documentation and SOPs.

Sesen is certified to ISO 17100 for translation services and ISO 13485:2016 for medical device quality management. Our processes meet international standards for quality, accuracy, data security, and risk control in life sciences content.

By aligning linguistic services with established regulatory frameworks, Sesen helps sponsors and CROs deliver compliant, inspection-ready training materials across global clinical sites.

Case Studies and Real-World Examples

Sesen has supported many clinical trials with high-volume, time-sensitive translations of site training materials across global regions. Our work spans therapeutic areas including oncology, rare diseases, vaccines, and CNS disorders, with proven success supporting sponsors and CROs from study startup through site activation.

Example: Translating Site Training Materials for a Phase III Oncology Trial Across 8 Countries

A global pharmaceutical company engaged Sesen to translate site training content for a Phase III oncology study spanning Europe, Asia, and Latin America. Deliverables included multilingual SOPs, investigator meeting slide decks, onboarding guides, and eLearning modules in 12 languages. The materials were formatted for direct upload into the sponsor’s LMS, supporting rapid site onboarding and compliance with ICH GCP and local ethics guidelines. Sesen completed the project within three weeks, meeting all regulatory, quality, and timeline requirements.

To learn more about our clinical trial translation experience and outcomes, please contact us or explore our full case study library.

Why Choose Sesen

Sesen is a trusted partner for clinical trial sponsors and CROs seeking high-quality translation of site training materials. Our deep specialization in life sciences and commitment to regulatory alignment ensure that multilingual training content is delivered with precision, speed, and consistency across global regions.

We specialize exclusively in life sciences translation. Our team understands the scientific, regulatory, and operational complexities of clinical trials and brings this knowledge to every project we manage.

All translations are performed by native speakers with subject matter expertise in clinical research. Our linguists are trained in GCP principles and have experience working with study protocols, site manuals, and onboarding content.

We have a strong track record delivering multilingual training solutions for leading pharmaceutical companies and global CROs. Our references include complex, multi-country studies across oncology, immunology, rare diseases, and more.

Sesen supports global site training programs in over 150 languages. We localize materials for both high-priority markets and emerging regions while maintaining consistency across all target languages.

From study startup to closeout, each project is managed by a dedicated clinical localization expert. Our project managers serve as a single point of contact, ensuring responsiveness, transparency, and accountability at every step.

Sesen delivers the experience, scale, and specialization required to help sponsors and CROs train clinical sites effectively and compliantly across global trials.

Related Services

Sesen offers a full suite of specialized translation and localization services to support every stage of global clinical trials. The following related services complement our site training materials translation capabilities and can be seamlessly integrated into your broader clinical documentation workflows.

These services are often delivered alongside site training content as part of comprehensive study startup localization programs.

  • Clinical Trial Translation Services

    Comprehensive translation support for protocols, case report forms, patient-facing materials, and regulatory submissions. Designed to meet the needs of global sponsors and CROs conducting multinational trials.

  • eHealth and mHealth Localization

    Localization of mobile health applications, eLearning modules, and digital engagement tools for healthcare delivery and clinical trials. We support accessibility across platforms, devices, and global languages.

  • GCP Compliance Translation

    Translation of compliance-critical documents and training content aligned with ICH E6 (R2) and regional regulations. Supports inspection readiness and consistency in GCP adherence across study sites.

  • Informed Consent Form Translation

    Accurate, culturally sensitive translation of informed consent forms for patient enrollment. Includes back translation, readability validation, and support for ethics committee approval.

  • Label Review and In-Context QA

    Specialized QA services to verify linguistic and formatting accuracy of training content, labels, and UI elements in real-world environments such as LMS platforms and digital apps.

Explore these services to build a unified, end-to-end localization strategy that drives site readiness, patient engagement, and compliance across global clinical operations.

Frequently Asked Questions

Sesen maintains a full version history of all translated content and can efficiently apply updates when protocols change. We use translation memory to minimize turnaround time and ensure consistent terminology across new and existing content. Updated materials are revalidated through our QA workflow before delivery.

Yes. We localize SCORM-compliant modules (including SCORM 1.2 and SCORM 2004) as well as courses built in Rise 360, Storyline, and other authoring tools. Our team preserves course structure, interactions, and embedded media to ensure multilingual versions function identically to the original, especially for use in site training environments such as LMS platforms and investigator portals.

Yes. We offer back translation, reviewer feedback incorporation, and reconciliation workflows as required by IRBs, ECs, or sponsors. These services are often applied to informed consent training, SOPs, or any site-facing training material that requires bilingual validation.

Turnaround time depends on volume, content type, and number of target languages. For most site training projects, we can deliver translated materials in 5 to 10 business days for up to 10 languages. Rush options are available based on study timelines and launch requirements.

Site training translation focuses specifically on materials used to onboard and instruct investigator teams and clinical site staff. These include SOPs, onboarding decks, GCP compliance modules, and LMS-based content tied to protocol adherence. Other types of clinical trial training may target sponsor-side teams, vendors, or technology partners. Sesen specializes in translating site-facing materials that directly support study startup and regulatory compliance.

Looking for translation support beyond site training? Explore our Training Translation Services for broader clinical trials and internal onboarding needs.

Ready to Translate Your Site Training Materials?

Partner with Sesen to deliver accurate, compliant, and multilingual training content across all your global trial sites. From SOPs to eLearning modules, we help your clinical teams stay aligned and inspection-ready in over 150 languages.

GET A QUOTE GET A QUOTE
SPEAK TO AN EXPERT SPEAK TO AN EXPERT